The first results of an objective assessment of the safety of emergency antihypertensive therapy at the pre-hospital stage

Abstract

We studied the possibilities of urgent monitoring of blood pressure and an objective assessment of its results at the pre-hospital stage. Of the 105 patients included in the study, 6 were excluded for technical reasons and 8 due to additional antihypertensive drugs. For emergency antihypertensive therapy, two-component combinations were used: captopril+furosemide, moxonidine+furosemide, moxonidine+nifedipine (if there was no intolerance to any of the studied drugs, they were prescribed using random numbers), blood pressure monitoring was simultaneously started, which lasted for a day. The stability of the antihypertensive effect, the frequency of excessive lowering of blood pressure in relation to its target value was evaluated. It was shown that the use of blood pressure monitoring techniques from the first minutes of sublingual use of various combinations of antihypertensive agents allows objectively assessing and documenting the safety of the effect of emergency therapy.