Abstract

1. The development of technology is a double-edged sword. Gene-editing technology, for example, has been widely used to treat diseases, predict drug targets and improve crops. CRISPR Cas-9 technology has made gene editing easier. However, the application of CRISPR technology to assisted reproductive technology (ART) is far from mature. When the human genes are changed, there may be unexpected outcomes that cannot be fully controlled. Further, ethical issues arise when this technology is not primarily used to eliminate severe diseases but becomes a business practice instead. If human beings can interfere with natural selection and “select” their offspring, or pay to have “designer babies”, the technology “may create a genetic aristocracy and lead to new forms of inequality”.1 In short, the use of this technology in human reproduction presents serious scientific and ethical issues. 2. The preamble to the Universal Declaration on the Human Genome and Human Rights adopted by the United Nations Educational, Scientific and Cultural Organization in 1997 (UNESCO Declaration) demands that:

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