Abstract
Relevance:Several studies have shown that non-intubation surgical interventions, especially, have proven themselves well in patients with low reserve of the cardiovascular and respiratory systems, as well as in the diagnosis of interstitial lung diseases.
 The study aimed to describe the experience of introducing into clinical practice surgical interventions without intubation on spontaneous breathing for malignant neoplasms of the lungs and mediastinal organs.
 Methods: two clinical cases are described of the main points of the anesthesia and technical features of surgical intervention.
 Results: A surgery in two patients with peripheral lung cancer was performed. In the first case, the operation included NI-VATS on the right and the resection of the upper (S2) and lower lobe (S6, S9); in the second case – NI-VATS on the right, lower lobectomy, and lymph node dissection. Based on the results of histological examination, both patients were diagnosed with NSCLC in the initial stages. Postoperative chemoradiotherapy is not indicated. The patients were registered at the dispensary in clinical group III.
 Conclusion: As the literature data and our preliminary results of NI-VATS show, surgical interventions in the surgical treatment of lung cancer have places to be and should be widely introduced into clinical practice in oncothoracic departments of the Republic of Kazakhstan.
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