Abstract
Chick embryos were inoculated with measured doses of various strains of the agents of trachoma and inclusion blennorrhoea, and the number of infective organisms they contained was determined at intervals during the first 4 days after inoculation. From curves of the yield of agent at different times relative to the dose inoculated, it was evident that the lag phase before the exponential phase of growth began was shorter for fast-killing—and more virulent—variant strains than for slow-killing strains, and the difference was statistically significant; and that variant strains multiplied faster during the exponential phase of growth and produced then- highest titres sooner.
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