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Abstract
Background: Gastroesophageal reflux disease (GERD) is a disease of the XXI century, affecting the population in the developed countries. There is a clear tendency to increasing of gastroesophageal reflux disease among people of young age.Aim: The aim of the study is to determine the characteristics and role of psychosomatic and vegetative state disorders in the pathogenesis of GERD with concomitant obesity.Materials and methods: 50 young patients with GERD were examined during the study. Depending on the presence or absence of concomitant obesity, two groups were formed. They underwent pH-metery, ultrasonic scanning. State of psycho-somatic, vegetative statuses and quality of life we determined by the questionnaires of Beck, Spielberg, Sheehan, Wayne.Results: During the ultrasound examination we determined the esophageal opening diameter, the thickness of esophageal wall, the esophagus width in the lower one third of the esophagus differed significantly in 2 groups of patients (p<0.05). In the group of the GERD patients with concomitant obesity the sharp increase of depression level was found, comparing with both the standard and the second group (p<0.05). It wasnt found the significant difference amount other figures of vegetative and psychosomatic statuses in 2 groups of patients (p>0.05). The patients with GERD of both groups had significantly higher level of motor-evacuation and psycho-vegetative disorders comparing with healthy people (p<0.05).Conclusion: GERD patients have pronounced motor-evacuation disorders and significantly greater manifestations of psycho-vegetative disorders which were more pronounced in gastroesophageal reflux disease patients with concomitant obesity.Bangladesh Journal of Medical Science Vol.14(2) 2015 p.142-145
Highlights
According to recent epidemiological data, there is a clear tendency to increasing of gastroesophageal reflux disease (GERD) rate[1,2] and its spreading especially among young people
The main symptoms noticed by patients were heartburn (90% of the cases), pain in the epigastric region (80%), regurgitation (60%), extraesophageal manifestations of Gastroesophageal reflux disease (GERD) (20%), dysphagia (6%)
We found the reliable differences in the indices of the ultrasound examination and psychosomatic condition of the GERD patients with concomitant obesity compared with the control group, and we did not found any significant differences in the indices between the patients of the first and second groups
Summary
According to recent epidemiological data, there is a clear tendency to increasing of gastroesophageal reflux disease (GERD) rate[1,2] and its spreading especially among young people At this stage, GERD is a medical and a social problem, leading to the formation of significant complications, including Barrett’s esophagus, the decrease of quality of. 2. Daria Kornienko, PhD student, Dept of Therapy, Rheumatology and Clinical Pharmacology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine. The first group included patients with GERD and obesity, 14 (56%) men and 11 (34%) women aged from 19 to 27 years old, the average age was 22±1.96 years old. The second group included patients with GERD without comorbidity, 15 (60%) men and 10 (40%) women aged from 18 to 25 years old, the average age was 21±0.56 years old. The study found that concomitant obesity aggravates the clinical manifestations of GERD, ultrasonic parameters and causes higher levels of depression[6,7]
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