Abstract
Abstract. Features of IgG and IgE immune response for opportunistic microbes of pharynx biotope in children with pharyngeal lymphoid hypertrophy and recurrent acute respiratory infections have been studied (base group). The ob tained data were compared with similar results for healthy children. It was shown that in children of base group in biotope of pharynx prevailed S. pyogenes, S. pneumoniae, S. mutans, P. vulgaris and C. albicans. It was demonstarted that in children of base group the IgG immune response was mainly induced by S. pyogenes, S. pneumoniae, B. catharrhalis and H. influenzae; and the IgE immune response — by S. pyogenes, S. pneumoniae, S. aureus and H. influenzae. The role of polyclonal induction of immune response to S. pneumoniae in pathogenesis of pharyngeal lymphoid hypertrophy and recurrent acute respiratory infections in children of early and preschool age has been detected.
Highlights
It was demonstarted that in children of base group the IgG immune response was mainly induced by S. pyogenes, S. pneumoniae, B. catharrhalis and H. influenzae; and the IgE immune response — by S. pyogenes, S. pneumoniae, S. aureus and H. influenzae
ORIGINAL ARTICLESShabaldina E.V.a, Shabaldin A.V.a,b, Lisachenko G.V.a, Drozdova M.V.c, Riazantsev S.V.c, Simbirtsev A.S.d a Federal State Budgetary Educational Institution of the highest vocational training Kemerovo State Medical Academy of Ministry of Health of Russia; b Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases» under the Siberian Branch of the Russian Academy of Medical Sciences; c Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech the Ministry of Health of Russia; d Saint-Petersburg State Federal Scientific Research Institute of especially pure biological products of Federal Medical Biological agency
Summary
Отмечена роль поликлональной индукции на S. pneumoniae в патогенезе гипертрофии миндалин лимфоидного глоточного кольца и рецидивов острых респираторных инфекций у детей раннего и дошкольного возрастов. Кафедрой оториноларингологии и клинической иммунологии ГБОУ ВПО Кемеровская государственная медицинская академия МЗ РФ, г. Кемерово; Шабалдин А.В., д.м.н., ассистент кафедры оториноларингологии и клинической иммунологии ГБОУ ВПО Кемеровская государственная медицинская академия МЗ РФ, ведущий научный сотрудник Отдела экспериментальной и клинической кардиологии НИИ Комплексных проблем сердечно-сосудистой патологии СО РАМН, г. Целью настоящего исследования было определение особенностей гуморального иммунного ответа на антигены условно-патогенной микробиоты, преимущественно глоточного биотопа, у детей с гипертрофией миндалин лимфоидного глоточного кольца; с дальнейшей интерпретацией данных с позиции патогенеза вторичных иммунодефицитов у детей раннего и дошкольного возрастов
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
