Abstract
Depression is one of the most common mental disorders. It refers to a kind of mood disorder with significant and lasting depression as the main clinical symptoms caused by various reasons. Its core symptoms are depression, loss of interest, lack of energy, often accompanied by physical symptoms, cognitive symptoms and so on. Serious patients have the risk of self injury and suicide. Most drug treatments focus on changing neurotransmitter activity in the brain, and Probiotics are a kind of active microorganisms which are beneficial to the host. They are colonized in the human intestinal tract and reproductive system and can produce exact health effects, thus improving the balance of the host's microecology and playing a beneficial role. Ingestion of certain probiotics seems to be a potential treatment for depression.
Highlights
Depression is a type of mood disorder whose main clinical features are significant and lasting depression, delayed thinking, decreased willpower, cognitive impairment, and physical symptoms
A large number of studies have confirmed that the intestinal flora and depression are closely related, but the cause and effect of the relationship are still inconclusive
It may be that certain events or stress trigger emotional changes, and these emotional changes subsequently change the gut microbiota
Summary
Depression is a type of mood disorder whose main clinical features are significant and lasting depression, delayed thinking, decreased willpower, cognitive impairment, and physical symptoms It has a high incidence, high recurrence, high suicide rate and high disability rate and other characteristics[2]. Used treatments for depression have a high rate of ineffectiveness and slow onset, and cause serious discomfort and side effects. These treatments make depression patients unable to work normally, and bring serious economic burdens to patients and reduce the quality of life[6]. This article starts with the influence of intestinal flora on depression and possible mechanisms and aims to explore the preventive and therapeutic effects of changes in intestinal flora on depression, providing more effective and less costly treatment with less side effects for patients with depression in the future
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