Abstract
In the present report, Asterias rubens Fc DNA Sequence was analysed from its transcriptome in bioinformatics; Identities occurred with other sea stars such as Patiria miniata and specially with mammals’ proteins. Identities with Fc receptor mammal IGE was found.
Highlights
Animal C-type lectins are involved in such functions as extracellular matrix organization, endocytosis, complement activation, pathogen recognition, and cell-cell interactions
Various vertebrate type 1 transmembrane proteins including macrophage mannose receptor, endo180, phospholipase A2 receptor, and dendritic and epithelial cell receptor (DEC205) have extracellular domains containing 8 or more CTLDs; these CTLDs remain in the parent model
A similar conformation is seen in the macrophage mannose receptor CRD4's putative non-sugar bound form of the domain in the acid environment of the endosome
Summary
The aim of this work is to analyse Fc DNA sequence which was discovered in 2016 [1] from Starting material (dna) sequence in 5’-3’: TCCATTAGGGCAATGAGTGGGACTGCGCGGCTTGG CACAGATCATCCCTTTTCTATCACGACACCTCGAGT CTTTCCACTTGCCGTTGCTAATCTGTAATGCCACAC AGTTATTCTCCAATGATTCGACTCCAGACAGCTCAG TTTGCTCTTCTTCGATGAAGTTCGTGTAGTTGACGG GGGAATCGTTTGACCATTTCCAATCGCTTTCGTTGT GTGTATCATGGAGCCCGATCCACACGTCCCTGTCA ATTAGGTCGGTAAGAAAATCATTAATTTCTTGGTCA GTGATGGCGACCAGCCTAGCGCCGTCGTATTTAGT GCACTTCTGTTCAGCATCGACCCAGCGTGCTACATC GTCTGGAATCCAGAAGCATTCATCACGGAAGAGAT GGCCGTTGTTTAGGCAGTACTGTGGTTGACCAC GTACTGTTTGAAGAAGATGAGCTGACCCAATAACC ATCATCATCACGAATGGAATCATTGTGAATTTGTTT GAGATACGTCCGATACGTCCGTCCGTAGATGAAAA AACTGCCGAAGTCTCTCACATAATTCCACCAGGCA TTGTTGATGCCTTGCTGCTCTATGGTTGATGCTTGG TGGCAGTCCACGAAAGAATGTGCAGTTAGGGAAAG TCCAGCTTGTATATCTC Bioinformatics data were performed according MarchlerBauer et al [2,3,4]. Optimization: we used highly similar sequences (mega blast) We recall that molecule type was dna; the query length of 654 2 sequences were selected as shown in the table1: significant aligments were found. Predicted: Asterias rubens macrophage Asterias rubens 1197 1197 100% 0.0 mannose receptor 1 like (LOC117293835) mRNA BlastX original sequence: The query length is 654in this DNA molecule: non-redundant protein sequences were used as Database (nr).
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