Abstract
Lorenz von Seidlein discusses the study by Katherine Halliday and colleagues and explores the reasons why a school-based screening and treatment strategy for malaria might have failed. Please see later in the article for the Editors' Summary
Highlights
Falciparum malaria incidence is declining in many countries including in the formerly hyperendemic regions of subSaharan Africa [1]
This Perspective discusses the following new study published in PLOS Medicine: Halliday KE, Okello G, Turner EL, Njagi K, Mcharo C, et al (2014) Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya: A Cluster Randomised Trial
The results cannot be attributed to methodological uncertainty, a frequent cause of negative study outcomes, since the trial was conducted in a large sample of schools according to the highest procedural standards
Summary
Falciparum malaria incidence is declining in many countries including in the formerly hyperendemic regions of subSaharan Africa [1]. Malaria control and elimination efforts continue to optimise the case management of patients as they present for health care whilst investigators search for a more aggressive approach that is feasible and effective. One strategy is to routinely screen the population and treat those who are infected, irrespective of whether they have symptoms or not. This strategy has been recommended by international health organizations on the basis of expert opinion and models [2]
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