THE FACTOR OF IONIZING RADIATION AND THYROID CANCER IN WOMEN IN THE ALTAI KRAI

Abstract

The purpose of the study was to study the dynamics of the incidence of thyroid cancer in the female population of the Altai Territory during the period of 1992-2016. Studies were performed with the use of data of the patient register of thyroid cancer, including information on 3026 women, with the use of methods of modern medical statistics. Intensive and standardized indices were calculated for the female population, resided near to traces of nuclear explosions executed at the Semipalatinsk test site, in the zone of the most significant radiation doses (the Main group). As a comparison, incidence rates of the remaining population of the Altai Territory (the Comparison group) and average values for the region were used. The article presents results of a descriptive epidemiological study of the incidence of thyroid cancer in the Altai Territory over 25 years (1992-2016). The results of the probabilistic association of the incidence of thyroid cancer with the ionizing radiation factor due to nuclear tests at the Semipalatinsk test site were obtained. The dynamics of the incidence of thyroid cancer by the data for five-years periods (averaged data): 1992-1996; 1997-2001; 2002-2006; 2007-2011 and 2012-2016 was studied in various territories of the Altai Territory: both on the traces of nuclear explosions - the main group, and in the rest territory (the comparison group), indices of average values for the regions. There were revealed the dynamics of the incidence of thyroid cancer in tens of years after nuclear tests in the population living in the zone with the most significant doses of radiation and its gradual decrease, due to rehabilitation measures. New approaches to the formation of high cancer risk groups for thyroid cancer in the Altai Territory are substantiated.