The F-18 FDG PET/CT evaluation of the metastatic adrenal lesions of the non-lung cancer tumors compared with pathology results

Zehra Pınar Koç,Pınar Pelin Özcan,Tuba Kara,Emel Sezer,Kadir Eser

doi:10.1186/s43055-021-00663-2

Zehra Pınar Koç, Pınar Pelin Özcan + Show 3 more

Open Access

https://doi.org/10.1186/s43055-021-00663-2

Copy DOI

Abstract

BackgroundThe aim of this study was to evaluate the role of F-18 FDG PET/CT imaging in the diagnosis of primary and metastatic adrenal tumors that originate from non-lung cancer primary tumors.ResultsF-18 FDG PET/CT images of patients (8 male and 6 female; mean: 55.36 ± 16.2 years old) who attended with the diagnosis of primary or adrenal metastatic lesions other than lung cancer metastasis were evaluated in a retrospective manner. The diameter of the adrenal lesions was mean: 23.93 ± 36.6 mm with SUVmax levels of mean: 9.98 ± 7.8. The primary site of 2/3 of the patients with unknown primary was the adrenal gland, and in one of the patients primary tumor remained unknown during follow-up.ConclusionsAccording to the results of this study, F-18 FDG PET/CT has high diagnostic performance in the diagnosis of the adrenal gland primary and metastatic lesions, which originate from non-lung cancer tumors. Further studies in the larger series are warranted.

Highlights

The most common tumor that metastasizes to the adrenal gland is lung carcinoma; gastrointestinal tumors may metastasize to the adrenal gland
Metastatic and primary tumors of the adrenal gland have significant fluorodeoxyglucose (FDG) uptake, and these tumors might be visualized by F-18 FDG positron emission tomography (PET)/computerized tomography (CT)
Among the patients who were referred for primary tumor investigation; the primary site of 2/3 patients was the adrenal gland and 1 patient remained unknown

Summary

Introduction

The most common tumor that metastasizes to the adrenal gland is lung carcinoma; gastrointestinal tumors may metastasize to the adrenal gland. Metastatic and primary tumors of the adrenal gland have significant fluorodeoxyglucose (FDG) uptake, and these tumors might be visualized by F-18 FDG positron emission tomography (PET)/computerized tomography (CT). There are several reports about the diagnostic performance of F-18 FDG PET/CT in the discrimination of malignant and benign adrenal lesions [1]. The diagnostic utility of F-18 FDG PET/CT in metastatic adrenal lesions has been addressed by multiple studies. The aim of this study was to evaluate the role of F-18 FDG PET/CT imaging in the diagnosis of primary and metastatic adrenal tumors that originate from non-lung cancer primary tumors

Objectives

Methods

Results

Conclusion