Abstract

Objective To observe the expression of mehmocortin 4 receptor (MC4R) gene in human lung cancer.Methods The samples were obtained from 15 cases with lung cancer specimens.Semiquantitative reverse transcription-polymerase chain reaction (RT-PCR) strategies and Western blot were used for analyzing the MC4R mRNA and protein expression in 15 samples and adjacent noncanerous tissues.Results MC4R mRNA and protein expression was increased in 80.0% of human lung cancer and in 26.7% of adjacent noncanerous tissues (P < 0.05).Conclusion MC4R activation might be in human lung cancer.MC4R gene may play some roles in the pathogenesis of human lung cancer. Key words: Lung cancer; Mehmocortin 4 receptor

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.