Abstract

Meeting abstracts This study is to investigate which Toll Like Receptors (TLRs) are expressed on human ovarian cancer cell lines and to evaluate the effect of TLR expression on the growth of ovarian cancer cells. Four human ovarian epithelial carcinoma cell lines SKOV3 (clear), OVCAR3 (serous

Highlights

  • This study is to investigate which Toll Like Receptors (TLRs) are expressed on human ovarian cancer cell lines and to evaluate the effect of TLR expression on the growth of ovarian cancer cells

  • To find whether the expression of TLRs is functional on human ovarian cancer cell lines, cytokines (IL-6, IL-10, TNF-a, IL-12, and IFN-g) were investigated

  • The expression and biologic function of TLRs are different in each ovarian cancer cell line

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Summary

Open Access

The expression and function of toll-like receptors (TLRs) in ovarian cancer cell lines. Shin-Wha Lee1*, In-Kyung Lee, Sumin Kim, Sang-Eun Lee, Ha-Young Lee, Dong-Woo Kang, Yong-Man Kim. From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA. From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA. 4-8 November 2015

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