Abstract

BackgroundYoung people have a higher prevalence of loneliness than other age groups, and they are also at risk of depression. Quantitative studies describe a bidirectional association between loneliness and depression, but there is limited understanding of how these influence each other. Little is known about the experience of loneliness among young people with depression. Qualitative approaches may help understand the relationship between loneliness and depression among young people, and how to intervene to improve outcomes. We aimed to conduct a meta-synthesis to understand the complex inter-relationship between loneliness and depression among young depressed people by synthesising evidence from a systematic review of qualitative studies.MethodsWe conducted a meta-synthesis of qualitative studies capturing experiences of loneliness among young people with depression. We systematically searched six electronic databases for selected search terms, critically appraised eligible studies, and analysed the data from included studies using the approach of thematic synthesis. We used feedback from an inter-disciplinary research workshop to improve reflexivity.ResultsOur inclusion criteria identified fourteen studies. Our analysis identified four themes: (1) social withdrawal due to poor mental health, (2) non-disclosure of depression contributing to social distance, (3) the desire to connect, and (4) paradoxes of loneliness and depression. These themes illustrated a range of pathways between depression and loneliness, and a sense of how these might be mutually reinforcing. Our findings suggest that where depressed individuals engage in certain behaviours (withdrawing; not confiding) for a range of reasons, this can lead to feelings of loneliness, an awareness of which worsens their mood, thus perpetuating their depression.ConclusionsYoung people with depression experience loneliness as an insurmountable distance between themselves and others. Our findings identified non-disclosure of depression, and the debilitating nature of the depressive symptomatology, as factors perpetuating a vicious cycle of loneliness and depression. They suggest that approaches to tackling the problem might include helping young people communicate about their depression to trusted friends and educating their social networks in how to support them. The wider research literature suggests that cognitive interventions may have a role in shifting maladaptive cognitions about their social world.

Highlights

  • Young people have a higher prevalence of loneliness than other age groups, and they are at risk of depression

  • Following full text review of the remaining 188 studies we excluded 177 based on our exclusion criteria, included eleven studies and added three more based on hand searching the references from the selected studies, identifying 14 eligible studies [24, 41,42,43,44,45,46,47,48,49,50,51,52,53], which we included in this meta-synthesis

  • Thematic synthesis Our thematic synthesis of 14 eligible studies identified four analytic themes: (1) social withdrawal due to poor mental health, (2) non-disclosure of depression contributing to social distance, (3) the desire to connect, and (4) paradoxes of loneliness and depression

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Summary

Introduction

Young people have a higher prevalence of loneliness than other age groups, and they are at risk of depression. We aimed to conduct a meta-synthesis to understand the complex inter-relationship between loneliness and depression among young depressed people by synthesising evidence from a systematic review of qualitative studies. Longitudinal studies demonstrate that loneliness increases the risk of becoming depressed [7,8,9], and worsens depressive symptoms amongst those who are already depressed [10], and that loneliness and depression influence each other reciprocally [11]. This means that people who are lonely are more likely to be become depressed, and that their depression reinforces their loneliness. The mechanisms underlying this complex inter-relationship between loneliness and depression are unclear and need further investigation, in young people

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