Abstract
The expansion of the compressed tablets in diameter and thickness due to their sorption of moisture has been studied, using starch and microcrystalline cellulose tablets.Of the starch tablets, the values of equilibrium volume expansion were very low as compared with the equilibrium moisture contents at low relative humidities below 20%. Above this relative humidity, the values of volume expansion were approximately at 1cm3 per gram of the sorbed water.In the kinetic measurement under different conditions of relative humidity, the rate constant of moisture sorption increased with increasing relative humidity. The values of rate constants of volume expansion were approximately equal to those of moisture sorption.For the microcrystalline cellulose tablets both the rate of moisture sorption and the rate of volume expansion decreased with increasing compaction pressure in tablet preparation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Society of Materials Science, Japan
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
