Abstract

From late nineteen nineties, the higher number of suitable renal transplant candidates has forced the transplant community to re-explore the whole spectrum of deceased donors after brain death (DBD) as well as after cardiac death (DCD); in practice, donors of older age and donors with more chronic diseases or “medical complexities”. This new kidney donor population – finally defined as extended criteria donors (ECD) – currently comprises on average 20 to 25%. In his seminal paper in 2003 on the introduction of ECD in the US, Metzger et al. covered all aspects of ECD transplantation. Even today, this paper still holds its truth on the issues of informed consent and selection of suitable transplant candidates. Since then, many reports discussed success and failure of ECD transplantation: higher rate of primary non-function, delayed graft function, rejection, higher costs and resources, and shorter longevity. This article is protected by copyright. All rights reserved.

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