Abstract
In dogs dysentery antigens are excreted by the kidneys following their intravenous introduction. The indicator of clearance determined for dysentery antigens increases with their repeated introduction or after preliminary immunization by dysentery vaccine. Excretion of antigens is connected with a transitional proteinurea. However there are no signs of disturbed function of the kidneys. As to the mechanism of excretion of these macromolecules—one may assume that they are excreted by filtration in glomeruli with the following partial reabsorption in the tubules. It is probable that increased filtration of the antigens and decrease of their reabsorption takes place in immunization.
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