Abstract
The validity, precision and practicability of two quantal and three quantitative methods of evaluating the immune responses of guinea pigs to diphtheria toxoids are compared. Of the five methods examined, a method based upon the use of multiple intradermal challenges provides as much statistical weight per animal as can be obtained from serum antitoxin titres but avoids the need for serum titrations. The statistical weight per animal of assays based on multiple intradermal challenges is generally twice that of assays based on subcutaneous challenge.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
