Abstract
The Evaluation of the Early and Late Postoperative Pancreatic Function and Nutritional Status: Central Pancreatectomy Versus Distal Pancreatectomy
Highlights
The pancreas has both exocrine and endocrine functions, and plays an important role in digestion and absorption by secreting pancreatic digestive enzymes in the pancreatic juice and releasing insulin into the blood
2) After distal pancreatectomy, body weight did not change significantly, while serum albumin was significantly increased until 36 months and hemoglobin A1c (HbA1c) was significantly increased at all times
3) Fatty liver, requirement for pancreatic digestive enzymes, and new-onset diabetes were all frequent following distal pancreatectomy, while none of these complications occurred after central pancreatectomy
Summary
The pancreas has both exocrine and endocrine functions, and plays an important role in digestion and absorption by secreting pancreatic digestive enzymes in the pancreatic juice and releasing insulin into the blood. Central pancreatectomy has been performed to preserve pancreatic function in selected patients with low-grade pancreatic tumors, but its shortterm and long-term efficacy for achieving this objective has been not so clear. Pancreatic exocrine function should be better after central pancreatectomy than after other types of pancreatectomy because more of the pancreas is retained. Because patients with low-grade pancreatic tumors can be expected to have longer survival after central pancreatectomy, preservation of pancreatic function over the long-term is required to maintain an acceptable quality of life. The importance of maintaining endocrine pancreatic function after pancreatectomy has been emphasized. Central pancreatectomy is performed to preserve pancreatic function in selected patients with lowgrade tumors. We evaluated short-term and long-term pancreatic function and nutritional status after central or distal pancreatectomy
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