Abstract
ObjectivesFournier’s gangrene (FG) is an devastating disease that affects the perineum and genitourinary region, and is commonly a result of poly-microbial infection. This study is aimed to determine the correlation between micrology and prognosis of FG in the past five years.MethodsThis study was a retrospective cohort study that was designed to study the trends in micrology and prognosis of FG. From the PubMed database, articles published in the recent 5 years (from Jan1st, 2009 to Dec 31st, 2013) were reviewed. A total of 19 articles (each with n > 30 and with thorough data descriptions in the topic of Fournier's gangrene), were enrolled in this study. The consolidated data was further analyzed by commercial statistical software (SPSS for Windows).ResultsThe twenty-two studies have covered FG cases from year 1981 to 2011, with a mean duration of 9.2 years. The total number of cases is 4,365. Majority of the cases are male (84.1%). The mean age and mortality rate is 51.8 ± 5 years old and 11.1 ± 8.9%, respectivly. The most commonly found pathogen is poly-microbial organism (54%), followed by Escherichia coli (46.6%) and Streptococcus (36.8%). The major risk factors are diabetes (43.7%), Body mass index of > 30 (40.7%), and hypertension (38.1%). Mortality rate in older patient group (age > 51.8 years old) is significantly higher than those of the younger group (22% vs. 5.5%, p = 0.0001).ConclusionsOlder patients with genital or perineal pain should be examined for crepitus dermis. When a patient is diagnosed with FG, swift consultation with surgeons and administration of broad-spectrum antibiotics are required in order to save the patient’s live.Electronic supplementary materialThe online version of this article (doi:10.1186/s40064-014-0783-8) contains supplementary material, which is available to authorized users.
Highlights
Fournier’s gangrene (FG) is a devastating necrotising disease that affects the perineum and genitourinary regions
Study has shown that males, especially in their 60 to 70s, are more often affected by FG when compared to other populations (Rodríguez Alonso et al 2000)
A retrospective cohort study was designed to investigate the correlation between micrology and prognosis of FG
Summary
Fournier’s gangrene (FG) is a devastating necrotising disease that affects the perineum and genitourinary regions. The common cause of FG is poly-microbial infections, where the diabetes mellitus is an attributing common risk factor (Shyam and Rapsang 2013). Study has shown that males, especially in their 60 to 70s, are more often affected by FG when compared to other populations (Rodríguez Alonso et al 2000). Aside from diabetes, other risk factors of FG include chronic alcoholism, renal failure, and obesity (Montoya Chinchilla et al 2009). The majorities of FG studies have shown that
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