The evaluation of health-related quality of life in patients with inflammatory bowel disease

Abstract

Objective To investigate the health-related quality of life (HRQoL) and its influencing factors in patients with inflammatory bowel disease (IBD).Methods The IBD patients underwent cross-sectional survey through Chinese version of inflammatory bowel disease questionnaire (C-IBDQ),the HRQoL of IBD patients were evaluated and analyzed with correlation analysis and multiple-linear regression analysis.Results A total of 100 IBD patients finished the questionnaire (UC 80,CD 17,ID 3).The overall score of HRQoL in IBD patients were (175.9±37.9),score of each item decreased,especially in the aspect of emotional function. There was no significantly difference in total scores of HRQoL between UC patients and DC patients (P＞0.05).The HRQoL total scores and each item score of patients in active period were significantly lower than those in remission period (149.4 ± 35.2,195.1 ± 26.7 ; P＜0.05).The HRQoL scores of patients with the duration less than one year were significantly lower than those over one year (P＜0.05).The HRQoL scores of severe patients were significantly lower than those of mild patients (P＜0.05).The HRQoL scores of patients whose medical cost mainly paid by themselves were lower than those paid by medical insurance,there were significant differences in social function and economic burden between these two groups.Multiple linear regressions analysis indicated that the influential factors of HRQoL were disease severity and activity,duration,and the payment.Conclusions The HRQoL of IBD patients are impaired in varying degrees.The influential factors of HRQoL were disease severity and activity,duration,and the payment.The HRQoL of IBD patients is obviously affected by economic burden. Key words: Inflammatory bowel diseases; Quality of life; Fees, medical