Abstract
The HbA1c test and the blood glucose test were compared in order to diagnose type 2 diabetes and determine the best cut-off point for the HbA1c test for optimal sensitivity in the population of Mosul city (inside it and some rural areas around it). The test was performed on a group of people between the ages of 40 and 85 who came to our laboratory after being diagnosed with or without type 2 diabetes by specialists in internal medicine and endocrinology. The HbA1c and FBS analysis were carried out between January 2020 and January 2021. And, by using ROC curve, the results for 80 individuals with an average age of 56 years produced a HbA1c test with a value of 6.8 percent, a sensitivity of 94 percent, compared to the result of 126 mg/ml for FBS as a diagnostic criterion , and the optimal cutoff point for HbA1c was reached for 6.86% in diagnosing disease diabetes type 2 was given the highest Yuden index by ROC curve analysis. Conclusion: We recommend that the optimal value of Hb2 with a percentage of 6.86 percent be used as the best test in diagnosing type 2 diabetes and obtaining the best medical and health care for the Mosul population.
Highlights
Diabetes is a chronic metabolic disease characterized by high blood sugar levels, and it causes significant damage to the nerves, blood vessels, kidneys, and eyes over time (IDF2013).[1]
By using ROC curve, the results for 80 individuals with an average age of 56 years produced a HbA1c test with a value of 6.8 percent, a sensitivity of 94 percent, compared to the result of 126 mg/ml for FBS as a diagnostic criterion, and the optimal cutoff point for HbA1c was reached for 6.86% in diagnosing disease diabetes type 2 was given the highest Yuden index by ROC curve analysis
For average blood sugar during the previous 120 days.[6] and the introduction of the HbA1c test as a diagnostic tool for diabetes and the cut-off point is the focus of controversy and study for many years, and many studies have been conducted in this field and for residents from different countries to reach the limit.[7]
Summary
Diabetes is a chronic metabolic disease characterized by high blood sugar levels, and it causes significant damage to the nerves, blood vessels, kidneys, and eyes over time (IDF2013).[1] Diabetes type 2 has become the most common and prevalent in the last four decades. The incidence of this disease has increased in all countries and at all levels. Controlled studies have documented a close relationship between HbA1c concentration and glycemic control In this regard, the people of Mosul should be provided with a high level of care in order to avoid spreading the disease. This study was carried out to determine the cut-off value and diagnostic tool for HbA1c levels in the Mosul population
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