Abstract
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative, established by the Office of Public Health Genomics at the Centers for Disease Control and Prevention, supports the development and implementation of a rigorous, evidence-based process for evaluating genetic tests, and other genomic applications for clinical and public health practice in the United States. An independent, nonfederal EGAPP Working Group (EWG), a multidisciplinary expert panel, selects topics, oversees the systematic review of evidence, and makes recommendations based on that evidence. This chapter describes the EGAPP processes, and details the specific methods and approaches used by the EWG.
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