Abstract
The commonest cause of thyrotoxicosis in childhood and adolescence is Graves’ disease, where autoantibodies stimulate the thyrotropin receptor and lead to excess thyroid hormone production. Excess thyroid hormone can have a deleterious effect on all body systems and so thyrotoxicosis should be considered in all young people with unexplained symptomatology. The diagnosis is confirmed by a combination of biochemical and immunological tests. Thyroid gland imaging may be useful in some circumstances. Treating Graves’ disease is difficult because of the chronic nature of the disorder and because the available options—anti-thyroid drugs, surgery and radio-iodine—all have significant disadvantages. Families need to be aware of the treatment options so that therapy can, where possible, be tailored to the individual. This patient's eyes “… were protruded from their sockets, and the countenance exhibited an appearance of agitation and distress …” (Caleb Hillier Parry, 1786).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
