Abstract
Antibiotics are substances that are produced by microorganisms that live from fungi that can fight or can fight other types of microbes. The use of higher antibiotics can be used in the use of antibiotics that are not rational. This research aims to improve the quality and quality of antibiotic use in inpatients at Patients with dyspepsia and complications of typhoid fever at TK Hijau Putri II Hospital, Kesdam I / BB Medan in 2018.The study was conducted descriptive descriptive with cross sectional research design with retrospective data collection conducted during the 2018 period. Quantitative evaluation research used the DDD (Defined Daily Dose) method and qualitative evaluation using the Gyssens category.The results showed that of the 120 patients using antibiotics, the quality assessment of the Gyssens category obtained results of 90% category 0 (rational), 10% category IIIA (duration too long). Evaluation of the amount by the DDD method (Daily Dose Determined) obtained the use of antibiotics with a DDD value / 1000 patient-day the highest was the fluoroquinolone group (ciprofloxacin and levofloxacin) with 56.4%, while for ciprofloxacin used 1,213 DDD / 1000 Patient-day and for levofloxacin have 1,000 DDD / 1000 Patient-days. Antibiotics for the third generation cephalosporins (cefotasim and ceftriaxone) with 43.14%, while for cefotasim have 713 DDD / 1000 Patient-days and for ceftriaxone have 1,000 DDD / 1000 Patient-days.
Highlights
Abstract−Antibiotics are substances that are produced by microorganisms that live from fungi that can fight or can fight other types of microbes
Quantitative evaluation research used the DDD (Defined Daily Dose) method and qualitative evaluation using the Gyssens category.The results showed that of the 120 patients using antibiotics, the quality assessment of the Gyssens category obtained results of 90% category 0 (rational), 10% category IIIA (duration too long)
Rsud Sukoharjo.Skripsi.Fakultas Farmasi.Universitas Muhammadiyah Jakarta.Hal 8 Widyasari I.(2016).Hubungan antara Kecemasan dan Tipe Kepribadian Introvert dengan Dispepsia
Summary
Dismotilitas saluran cerna bagian atas menimbulkan keluhan-keluhan saluran cerna berupa mual, muntah, nyeri ulu hati, rasa terbrakar didada, kembung, anoreksia. Menurut data Profil Kesehatan Indonesia 2007, dispepsia sudah menempati peringkat ke-10 untuk kategori penyakit terbanyak pasien rawat inap di rumah sakit tahun 2006 dengan jumlah pasien 34.029 atau sekitar 1,59%. Resistensi merupakan dampak negatif dari pemakaian antibiotik yang irasional, penggunaan antibiotik dengan indikasi yang tidak jelas, dosis atau lama pemakaian yang tidak sesuai, cara pemakaian yang kurang tepat, status obat yang tidak jelas, serta pemakaian antibiotik secara berlebihan. Penggunaan antibiotik dapat dinilai secara kuantitas dengan Defined Daily Dose (DDD) yang menunjukkan asumsi dosis rata-rata perhari penggunaan antibiotik untuk indikasi tertentu pada orang dewasa dan secara kualitatif dengan metode Gyssens berdasarkan data rekam medik dan kondisi klinis pasien (Faizah Binfar, 2019). DDD adalah suatu unit internasional yang dapat digunakan secara luas untuk menilai penggunaan obat termasuk antibiotik disarana pelayanan kesehatan (MG Sholih, 2019). Jumlah pemakaian antibiotik yang memiliki kode ATC (dalam gram) dikonversi ke dalam unit DDD kemudian dihitung dalam satuan DDD/1000 patients days (Kemenkes RI, 2011)
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