Abstract
The aim of human subjects research is to create generalizable knowledge that benefits future patients. Consequently, it risks sacrificing the interests of research participants for the greater good of society. Ethics guidelines exist to minimize this risk. Over the last decade, international biomedical research in the context of substantial healthcare inequalities has focused discussion on four ethical issues: (i) standards of care; (ii) informed consent; (iii) ancillary care obligations; and (iv) posttrial benefits (see table, right). It is appropriate to consider these issues relative to the Bucharest Early Intervention Project (BEIP) study (1), a randomized trial of the effects of moving institutionalized young children to foster care. Table Four main ethical issues in international research
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