The Equilibria for the Inosine–Calcium Hydroxide–Water and Inosine–Strontium Hydroxide–Water Systems

Abstract

Abstract Solubility data have been obtained for the inosine–Ca(OH)2–H2O and inosine–Sr(OH)2–H2O systems at 10 °C. Three different solid phases of the calcium salt of inosine were found in the former system. The first is the normal hemi-calcium salt, (inosine) 2·Ca·2H2O; the second, an abnormal salt, (inosine)3·Ca·3H2O, and the third, another abnormal salt, (inosine)4·Ca·9H2O. The former two salts have stable regions in the system, while the last one does not. The system including Sr(OH)2 is simple, and no other salt-formation was found except for that of normal hemi-strontium salt, (inosine)2·Sr·2H2O. The X-ray powder diffraction data of the above four salts are given. The solubilities of the two normal hemi-alkaline-earth-metal salts of inosine in water were determined at 10—60 °C and formulated as follows: Ca-salt, logS & = 0.00406·t - 0.4725 Sr-salt, logS & = 0.00551·t - 0.4116 where S represents the gram weight of anhydrous salt per 100 g of water.