Abstract

Intussusception is one of the most common causes of intestinal obstruction in young children. We report a retrospective, observational study of the epidemiology of intussusception in South Korea using the National Health Insurance Service-National Sample Cohort (NHIS-NSC). A cohort of newborns born between 2002 and 2008 was selected. The primary objective was to assess the incidence of intussusception in the pediatric population of Korea. The secondary objectives were to describe the basic epidemiological characteristics of intussusception and to identify risk factors. A total of 362 children were identified. The highest incidence of intussusception (2.6 per 1,000) was observed in children aged 1–2 years. A total of 58.8% of the children were male, and there was no significant difference in incidence according to the birth year (P = 0.804). Most of the children diagnosed with intussusception underwent air reduction, while only 0.6% had surgery. In all, 82.3% of the children were admitted to the hospital, 0.8% of them had to be admitted to the ICU, and the 6-month mortality was only 0.3%. In this retrospective, observational study, the incidence of intussusception was highest among children between 1 and 2 years of age. Most of the children underwent air reduction.

Highlights

  • Intussusception is one of the most common causes of intestinal obstruction in infants and young children

  • Observational study on the epidemiology of intussusception in South Korea

  • The NHIS-NSC contains information about the patients’ age, sex, and type of insurance; a list of diagnoses based on the International Classification of Diseases, tenth revision (ICD-10); the medical costs claimed; prescribed medications; treatments covered by the National Health Insurance; and hospital facility information

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Summary

Introduction

Intussusception is one of the most common causes of intestinal obstruction in infants and young children. It is a condition in which the proximal portion of the intestine invaginates into the more distal portion[1, 2]. The symptoms of intussusception include cyclic abdominal pain, vomiting, and bloody stools. It is usually diagnosed by radiologic means, such as ultrasonography (US). The reported incidence of intussusception in the pediatric population was 30–60 cases per 100,000 child-years in North America, Europe, and Australasia[2, 4,5,6,7], while

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