Abstract
ObjectivesTo analyze the epidemiological characteristics of COVID-19 related deaths in Wuhan, China and comprehend the changing trends of this epidemic along with analyzing the prevention and control measures in Wuhan.MethodsThrough the China’s Infectious Disease Information System, we collected information about COVID-19 associated deaths from December 15, 2019 to February 24, 2020 in Wuhan. We analyzed the patient’s demographic characteristics, drew epidemiological curve and made geographic distribution maps of the death toll in each district over time, etc. ArcGIS was used to plot the numbers of daily deaths on maps. Statistical analyses were performed using SPSS and @Risk software.ResultsAs of February 24, 2020, a total of 1833 deaths were included. Among the deaths with COVID-19, mild type accounted for the most (37.2%), followed by severe type (30.1%). The median age was 70.0 (inter quartile range: 63.0–79.0) years. Most of the deaths were distributed in 50–89 age group, whereas no deaths occurred in 0–9 age group. Additionally, the male to female ratio was 1.95:1. A total of 65.7% of the deaths in Wuhan combined with underlying diseases, and was more pronounced among males. Most of the underlying diseases included hypertension, diabetes and cardiovascular diseases. The peak of daily deaths appeared on February 14 and then declined. The median interval from symptom onset to diagnosis was 10.0 (6.0–14.0) days; the interval from onset to diagnosis gradually shortened. The median intervals from diagnosis to death and symptom onset to deaths were 6.0 (2.0–11.0), 17.0 (12.0–22.0) days, respectively. Most of the disease was centralized in central urban area with highest death rate in Jianghan District.ConclusionCOVID-19 poses a greater threat to the elderly people and men with more devastating effects, particularly in the presence of underlying diseases. The geographical distributions show that the epidemic in the central area of Wuhan is more serious than that in the surrounding areas. Analysis of deaths as of February 24 indicates that a tremendous improvement of COVID-19 epidemic in Wuhan has achieved by effective control measures taken by Wuhan Government.
Highlights
The outbreak of new infectious diseases in recent years has caused great losses to human health, quality of life and economy
Patients As of February 24, 2020, a total of 1833 unique deaths with COVID-19 were included in the analysis
The first death occurred on January 9, 2020
Summary
The outbreak of new infectious diseases in recent years has caused great losses to human health, quality of life and economy. In December 2019, a new coronavirus began to spread in Wuhan and even the whole country. On December 31, an alert was issued by the Wuhan Municipal Health Commission and a rapid response team was sent to Wuhan by the Chinese Center for Disease Control and Prevention (China CDC). Epidemiological investigation implicated that this pneumonia epidemic was different from the previous ones and Wuhan Huanan Seafood Wholesale Market may be a possible source of infection. On January 1, the Huanan Seafood Wholesale Market was shut down. On January 20, China’s “National Infectious Diseases Law” was amended to make 2019-novel coronavirus diseases (COVID-19) a Class B notifiable disease and its “Frontier Health and Quarantine Law” was amended to support the COVID-19 outbreak response effort. As of February 5, two newly established COVID-19 designated hospitals and several mobile cabin hospitals have been opened
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