Abstract
The use of language is one of the most vital traits that distinguish human from other species. The gene FOXP2 (fork head box P2) is relevant to the human ability to develop language. FOXP2 is situated on human chromosome 7q31, and its major splice form encodes a protein of 715 amino acids. It contains a glutamine rich region consisting of two adjacent polyglutamine tracts, encoded by mixtures of CAG and CAA repeats. Two functional copy of FOXP2 seem to be required for acquisition of normal language in human. The chimpanzee, gorilla and the rhesus macaque FOXP2 proteins are all identical to each other and carry only one difference from the mouse and two differences from the human protein, whereas the orangutan two differences from the mouse and three from humans. This gene is also important on particular aspects of cognition awareness or grammatical processing.
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