Abstract
Simian crease (SC), a single transverse crease that extends from across the palm of the hand. The presence of a single transverse palmar crease or the SC can be, but not always, a symptom associated with abnormal medical conditions. In dysmorphology, the clinical significance of variability of palmar creases especially SC are widely recognized and have occurred more frequently in patients with various congenital anomalies that are caused by genetic as well as environmental insults in the first half of pregnancy. SC has been studied extensively in children especially with Down’s syndrome (DS) where the incidence of SC is more than 63%. In this case report, two families are discussed with relevance to the presence of SC. The first family with two children with DS have no SC in any of them, whereas the second healthy family only the father who is a doctor by profession having an SC.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.