Abstract
Acid rate, resistance, short circuit current, P.D., Cl − transport, O 2 consumption and redox steady state were determined in frog or Necturus gastric mucosa under a variety of conditions. It was shown that measurements of ΔH/ΔO 2 under conditions of stimulation of acid rate by hormones in Necturus, or ion substitution in frog did not allow valid conclusions to be drawn as to acid mechanism. The simplest interpretation of the results of a series of experiments using redox inhibitors and phosphorylative inhibitors and uncouplers is that mitochondrially generated ATP is the obligatory energy source for H + transport, and that Cl − transport can utilize extramitochondrial sources of energy.
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