The Elliptical Aggregates – Idiopathic Granulomatous Mastitis

Anubha Bajaj,El-Sabbagh Ah

doi:10.14302/issn.2690-4837.ijip-19-3145

Abstract

Idiopathic granulomatous mastitis was initially scripted in 1972 by Kessler and Wolloch and is cogitated as an infrequent, benign, chronic inflammatory disorder. It commonly implicates females of reproductive age group, especially women who have breast fed in the preceding five to six years. Idiopathic granulomatous mastitis is commonly discerned in Asia and Mediterranean region although true incidence is undetermined. Diverse ethnicities delineate a diverse disease prevalence. Elimination of adjunctive causes of granulomatous inflammation makes idiopathic granulomatous mastitis a diagnosis of exclusion. As per the natural history, idiopathic granulomatous mastitis is designated as a self limiting disorder 1.

Highlights

Disease CharacteristicsEssentially an uncommon condition of obscure origin, granulomatous mastitis simulates an abscess or carcinoma breast on radiography
An infectious aetiology of granulomatous mastitis requires elimination as corticosteroids are contraindicated in infectious aetiologies [2,3]
Mechanism of inflammation in idiopathic granulomatous mastitis is comprised of an injurious deterioration of ductal epithelium followed by metamorphosis and luminal secretions within the lobular connective tissue

Summary

Introduction

An uncommon condition of obscure origin, granulomatous mastitis simulates an abscess or carcinoma breast on radiography. Mechanism of inflammation in idiopathic granulomatous mastitis is comprised of an injurious deterioration of ductal epithelium followed by metamorphosis and luminal secretions within the lobular connective tissue. Core needle biopsy of idiopathic granulomatous mastitis enunciates multiple aggregates of non- caseating epitheloid cell granulomas within and encompassing breast lobules, constituted of epitheloid histiocytes, lymphocytes, neutrophils and multinucleated giant cells.

Results

Conclusion