Abstract

The electrical resistance has been determined for aqueous channels through thick walls which separate electrolyte solutions of different concentrations under hydrostatic and osmotic pressure gradients. It is shown that the variation of the conductivity of epithelial layers under various constraints can be subjected to a similar analysis. Although the treatment is quantitative, concomitant morphological changes in the tissue could also take place which would introduce a non-predictive element. An awareness of both effects appears essential, when osmotic and/or hydrostatic pressure gradients are applied across epithelia.

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