The electrical and dielectric properties of human bone tissue and their relationship with density and bone mineral content.

Abstract

In this study, we examined the electrical properties of wet human cortical and cancellous bone tissue from distal tibia and their relationship to the wet, dry, and ash tissue densities. The resistivity and specific capacitance of both cortical and cancellous bone were determined for different frequencies and directions (orientation). The wet, dry, and ash tissue densities of the bone samples were measured, and the ash content was determined. Correlation and regression analysis was used to examine the possible relationships among the electrical properties and the tissue densities for cancellous and cortical bone specimens separately as well as for all of the bone specimens combined. Highly significant positive correlations (p < 0.001) were found between the wet density of bone and the dry and ash densities. The specific capacitance of the cancellous bone specimens in all three orthogonal directions showed significant (p < 0.01) positive correlations with the wet, dry, and ash densities. In general, the specific capacitance depended more on density for all bone specimens, and only a weak relationship was found between the resistivity of human cortical bone and density.