Abstract
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Highlights
The yields of products are typically low to moderate, but the simplicity of the reactions frequently recommends their use
Isolation of the product usually takes advantage of the high water solubility of the intermediate sulfate ester; acidification of the reaction mixture is followed by extraction of the unreacted starting material by an appropriate organic solvent
The sulfate ester remains in the aqueous phase
Summary
The yields of products are typically low to moderate, but the simplicity of the reactions frequently recommends their use. Isolation of the product usually takes advantage of the high water solubility of the intermediate sulfate ester; acidification of the reaction mixture is followed by extraction of the unreacted starting material (in the case of phenols) by an appropriate organic solvent. Hydrolysis of the sulfate ester in aqueous acid produces the (usually) organic-soluble dihydric phenol.
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