Abstract
The Efficacy of Xenograft Polymerized with Platelet Rich Fibrin Versus Autogenous Graft During the Secondary Alveolar Bone Grafting Of Alveolar Clefts: A Randomized Controlled Clinical Trial
Highlights
Secondary alveolar bone grafting (SABG) is considered to be an important comprehensive treatment for cleft lip and palate patientsduring the mixed dentition stage [1]
Materials and Methods: Twenty patients with unilateral alveolar cleft were divided into two groups: Autogenous grafts group (6 males, 4 females) with a mean age of 10.5 yrs, and Xenografts polymerized with (I-platelet rich fibrin (PRF)) group (5 males, 5 females) with a mean age of 9.8 yrs.After six months of grafting, gingival and periodontal clinical examination have been achieved at the adjacent teeth of the alveolar cleft area for all patients, while bone density was compared radiographically between alveolar cleft region and intact corresponding region within and between groups using (Cone Beam Computed Tomography) cone beam computed tomography (CBCT)
Whilethe second group showed no significant difference in the bone density values when comparing between the grafted alveolar cleft region (520 ± 170HU) and the intact corresponding area (510 ± 150HU)
Summary
Secondary alveolar bone grafting (SABG) is considered to be an important comprehensive treatment for cleft lip and palate patientsduring the mixed dentition stage [1]. SABG has many advantages likethe stabilization of maxillary dental arch, reaching to a continuous alveolar process, closing theoronasal fistula, facilitating the normal eruption of the impacted teeth into the grafted area, supporting the upper lip, and improving the esthetic appearance [2, 3]. There are many shortcomings associated with this type of bone grafting such as, donor site deterioration, infection, significant pain, high bone resorption rate, and increased hospitality time with the possibility of hematoma [7, 8]. These disadvantages led to search for alternative substances that are biocompatible, re-
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Dentistry and Oral Science
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
