Abstract
Aims: In this study, triamcinalone acetonide was applied topically in the tooth socket following surgic-al removal of teeth to evaluate its anti-inflammatory effect. Materials and Methods: Forty medically fit patients were selected with an age range between (18-50) years of both genders, non smoker, no pregnant or lactating woman. The patients were divided equally into a trial and control group. Surgical extraction was done for all patients. In the first group, the socket was covered with a piece of sterile gauze (2 X 2 cm) impregnated with triamcinalone acetonide ointment %1. In the control group, the extracted socket was covered with sterile gauze only. The sterile gauze was removed 24hrs postopera-tively. Postoperative pain and swelling were examined in 1st, 2nd and 7th days. Results: Mann-Whitney test revealed no significant difference in the pain level and swelling at the 1st day but with a significant difference in the 2nd and 7th days between both groups. Conclusions: The pH of saliva in male pa-tients with (RAU) was more toward acidic pH than normal male subjects.
Highlights
Pain and Swelling Assessment Pain and swelling assessment for each patient was examined in the 1st, 2nd and 7th days after extraction according to the following criteria: Pain: This was recorded by the patient himself using Visual Analogue Scale (VAS) [11,12] ranging from 0 to 10 where 0 stood for no pain, 1-3 = mild pain, 4-6 moderate pain and 7-10 severe unbearable pain
(14) In this study, 1% triamcinalone in orabase produced a reduction in pain and swelling in the 2nd and 7th day following surgical extraction when applied topically to the extracted socket compared to the control (p≤0.05)
This effect can be explained by the long, persisting 24-hour duration of action through complete absorption of triamcinalone from its site of application. [15, 16]Pelletier et al [2] and Robert et al [17] stated that the mean elimination half-life of triamcinalone was 4-6 day in knee joint. This observation regarding the effect may explain the significant reduction in pain and swelling at the 2nd and 7th post-operative day with the advantages of a minimal risk of single dose of corticosteroids. [2, 17] Markiewicz et al [18] found that preoperative administration of corticosteroid produce a mild to moderate reduction in edema and improvement in range of motion following third molar removal
Summary
All patients were instructed for good oral hygiene and simple home care. In case of severe unbearable pain the patients was instructed to take paracetamol tab. Patients were divided into two groups: Group I: In this group, socket was covered with a sterile piece of gauze ( 2 X 2 cm) impregnated with 1 cm Triamcinalone ointment 1% with orabase (Unipharma Syria) to be removed following 24hr. Pain and Swelling Assessment Pain and swelling assessment for each patient was examined in the 1st, 2nd and 7th days after extraction according to the following criteria: Pain: This was recorded by the patient himself using Visual Analogue Scale (VAS) [11,12] ranging from 0 to 10 where 0 stood for no pain, 1-3 = mild pain, 4-6 moderate pain and 7-10 severe unbearable pain.
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