The efficacy of salmeterol/fluticasone propionate inhaler for stable chronic obstructive pulmonary disease in elderly patients

Abstract

Objective To explore the efficacy of salmeterol/fluticasone propionate ( SFP ) inhaler for stable chronic obstructive pulmonary disease ( COPD ) in elderly patients.Methods 100 elderly patients were randomly divided into two groups.In addition to general treatment,the study group received inhaled SFP while the control group received inhaled beclometasone dipropionate.Pulmonary function indices including forced expiratory volume in 1 second ( FEV 1 ),forced vital capacity ( FVC ),FEV/FVC, and FEV1/predictive FEV1 were detected and the MRC scale was used in the two groups.Results The symptom of dysventilation improved at some degree in both groups.The study group was superior to the control group in MRC scale,FEV,and FEV/FVC [( 3.84 ± 0.78 ) vs.( 4.15 ± 0.82 ),( 11.54 ± 0.43 ) vs.( 1.47 ± 0.42 ),and (69.37 ± 5.12 ) ％ vs.( 64.36 ± 4.98 ) ％,with a statistical difference ( P＜ 0.05 ).Conclusions Salmeterol/flutieasone propionate inhaler can effectively improve pulmonary function and release dysventilation in elderly patients with table COPD. Key words: Salmeterol/fluticasone propionate; Inhalation; Chronic obstructive pulmonary disease