The efficacy of proliferative membrane stripping combined with retinal laser photocoagulation for the treatment of proliferative vitreoretinopathy on silicone oil-filled eyes

Abstract

Objective To evaluate the efficacy of proliferative membrane stripping combined with retinal laser photocoagulation for the treatment of proliferative vitreoretinopathy ( PVR ) on silicone oil-filled eyes. Methods The data of 66 eyes of 66 patients with PVR after vitrectomy combined with silicone oil tamponade surgery from January 2013 to June 2015 in our hospital were retrospectively analyzed. These patients received proliferative membrane stripping combined with retinal laser photocoagulation. The visual acuity before and after the surgery, central macular thickness, retinal reattachment, the timing of silicone oil removal and postoperative complications were observed and analyzed. Results The retinas were reattached in all 66 eyes after the surgery and no serious complication occurred. The removal of the silicone oil was within 3 months in 39 eyes ( 59.09% ) and 4 to 6 months in 27 eyes (40.91%). The membrane stripping operation was performed 2 to 4 times in 10 eyes ( 15.15% ). The recurrent retinal detachment occurred after the oil removal in 2 eyes (3.03%) and the silicone oil tamponade surgery was performed again to reattach the retina. The postoperative visual acuity improved significantly compared with preoperative visual acuity and the difference was statistically significant (χ2=14.85, P=0.0019 ). Before the surgery the mean thickness of central macular area was (352.70 ± 55.52) μm. Three months after the surgery the thickness reduced to (324.37±49.74) μm and the difference was statistically significant (t=7.591, P=0.000 ). Conclusion Proliferative membrane stripping combined with retinal laser photocoagulation for PVR on silicone oil-filled eyes is exactly effective. Key words: Proliferative membrane stripping; Laser photocoagulation, retinal; Vitreoretinopathy, proliferative; Silicone oil-filled eyes; Efficacy