Abstract
The hormone dihydro testosterone (DHT) and the catalyst 5α-reductase are key contributors to hair loss due to androgenetic alopecia (AGA). Also, dermal bacteria and their toxins have been implicated in hair loss. A preliminary study by the authors with six male volunteer subjects showed that ostrich antibodies against above causative substances were quite effective in promoting hair regrowth. The present study included 13 men and 4 women, with ages ranging from 39 to 78. Pre- and post-treatment hair counts were also incorporated into the study procedure. In all instances but one, the subjects had a hair-growth effect about 3 months after the antibody was applied to the scalp, and the study participants with hair growth were pleased with the results and with the ease of use of the antibody solution.
Highlights
Dihydrotestosterone (DHT) and 5α-reductase have been shown to be involved in the male pattern baldness of androgenic alopecia (AGA) [1] [2] [3]
A preliminary study by the authors with six male volunteer subjects showed that ostrich antibodies against above causative substances were quite effective in promoting hair regrowth
In all instances but one, the subjects had a hair-growth effect about 3 months after the antibody was applied to the scalp, and the study participants with hair growth were pleased with the results and with the ease of use of the antibody solution
Summary
Dihydrotestosterone (DHT) and 5α-reductase have been shown to be involved in the male pattern baldness of androgenic alopecia (AGA) [1] [2] [3]. It has been shown that reducing the production of DHT promotes hair growth in AGA [4]. Applied minoxidil and orally administered finasteride have been shown to be effective in countering the effects of DHT and reducing the production of DHT, respectively [5] [6] [7]. It has been suggested that abnormal propagation of pathogens such as dermal bacteria and their toxins induce hair loss [8]. We have so far developed a method to promote hair growth by suppressing hair loss-inducing factors using antibodies. Antibodies are immunoglobulins produced by β-cells when a foreign substance such as pathogens enters the body. The characteristic “antigen-antibody” reaction usually targets only the inducing antigen. Therapeutic antibodies are produced in mice, rabbits or cultured cells, and their production costs are very high
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