The Efficacy of New Chinese Diabetes Risk Score in Screening Undiagnosed Type 2 Diabetes and Prediabetes: A Community-Based Cross-Sectional Study in Eastern China.

Tao Mao,Xiaoning Li,Haijian Guo,Shiqi Zhen,Xuepeng Xu,Guoping Yang,Jiayan Chen,Chen Qu,Chu He

doi:10.1155/2020/7463082

Abstract

The New Chinese Diabetes Risk Score (NCDRS) is one of the recommended tools for screening undiagnosed type 2 diabetes in China. However, its performance in detecting undiagnosed diabetes needs to be verified in different community populations. Also, it is unknown whether NCDRS can be used in detecting prediabetes. In the present study, we aimed to evaluate the performance of NCDRS in detecting undiagnosed diabetes and prediabetes among the community residents in eastern China. We applied NCDRS in 7675 community residents aged 18-65 years old in Jiangsu Province. The results showed that the participants with undiagnosed diabetes reported the highest NCDRS value, followed by those with prediabetes (P < 0.001). The best cut-off points of NCDRS for detecting undiagnosed diabetes and prediabetes were 27 (with a sensitivity of 78.0% and a specificity of 57.7%) and 27 (with a sensitivity of 66.0% and a specificity of 62.9%). The AUCs of NCDRS for identifying undiagnosed diabetes and prediabetes were 0.749 (95% CI: 0.739~0.759) and 0.694 (95% CI: 0.683~0.705). These results demonstrate the excellent performance of NCDRS in screening undiagnosed diabetes in the community population in eastern China and further provide evidence for using NCDRS in detecting prediabetes.

Highlights

With an increasing incidence and economic burden [1, 2], type 2 diabetes mellitus (DM) has been a significant public health concern worldwide
The other major issue is the detection of prediabetes, including impaired glucose tolerance (IGT) and impaired fasting glycemia (IFG)
By using the LSD method, the New Chinese Diabetes Risk Score (NCDRS) scores of DM were higher than the scores of preDM (P < 0:001), and the scores of preDM were higher than the scores of normal glucose tolerance residents (P < 0:001)

Summary

Introduction

With an increasing incidence and economic burden [1, 2], type 2 diabetes mellitus (DM) has been a significant public health concern worldwide. The global prevalence (age standardized) of DM has risen to 8.5% in the adult population in 2014 [3] and has grown fast in low- and middle-income countries over the past decade. China is one of the countries facing serious challenges, with a prevalence of DM of 10.4% (World Health Organization, WHO 1999 criteria) in the population aged 18 and above in 2013 [4]. PreDM is a transition between normal glucose tolerance and diabetes, and it has been proved to be a critical high-risk factor of DM. The prevalence of preDM had reached 35.7% (American Diabetic Association, ADA 2003 criteria) in China in 2013 [4], which means that there may be a large number of patients with DM in the few decades. The same as above, most of the individuals did not realize that they were at high risk of developing DM [5]

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