Abstract

Recently, macro-focused ultrasound (MFU) has become a popular noninvasive esthetic treatment for facial laxity. However, there are no studies done that evaluated the use of MFU with a 2.0mm transducer for upper facial lifting. To evaluate the efficacy and safety of MFU with a 2.0mm transducer in the treatment of upper facial laxity in Thai patients. This was a prospective, evaluator-blinded pilot study with 34 Thai patients diagnosed with mild to moderate facial laxity. Patients were treated with a single session of MFU with 2.0mm transducer at the forehead, lateral and just below the eye area. Primary outcome was the clinical improvement of upper facial laxity graded by 2 blinded dermatologists at baseline, 1-week, 1-, 3-, and 6-month follow-up. Objective measurements including eyebrow height, upper facial volume, and textural irregularities were evaluated. Patients' self-assessment scores and adverse effects were also recorded. Out of 34 patients, 27 (79.4%) attended all follow-ups. Clinical improvement of upper facial laxity was observed as early as 1-week follow-up. Eyebrow height elevation was significantly increased at every follow-up (P=.000) with an average of 1.22mm at 6-month follow-up. Wrinkles improved significantly at 1-week and 6-month follow-up (P=.002 and P=.010, respectively). Skin roughness showed significant improvement at 6-month follow-up (P=.004). Majority of the patients (53.6%) reported marked improvement at 3-month follow-up. No serious adverse event was noted. Macro-focused ultrasound is a safe and effective treatment for upper facial laxity and skin textural irregularities in patients with mild to moderate degree of laxity.

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