The Efficacy of <i>Narasimha Rasayana</i> in Reducing Testosterone Deficiency in Adult Males

Abstract

Introduction: Testosterone deficiency is defined as the clinical condition characterized by deficient production of testicular testosterone resulting in various symptoms pertaining to somatic, psychologic and sexual domains. This condition was identified as a Vāta-Pitta Pradhana Avastha where the vitiated Vāta and Pitta Dōṣās take Sthana Samsraya in the Viguna Śukravāhasrōtas resulting in Śukra Kshaya along with its functional impairment causing symptoms involving both Sarīra and Manas. Methodology: This was a pre and post-test single group clinical study conducted in 20 male patients in the age group 30 to 60 years having AMS (Aging Males Symptom) score between 27 and 49 and serum total testosterone (TT) level below 450 ng/dL. The treatment protocol adopted was Pācana Dīpana with Aṣṭacūrṇa; Abhyantara Snēhana with Kalyāṇaka Ghṛta; Sarvānga Abhyanga (Tila Taila) and Bāṣpa Swēda; Kōṣṭ aśuddhi with Gandharvahasta Ēranda Taila and Rasāyana Prayōga with Nārasimha Rasāyana for 30 days. After completion of the study, the results were statistically analysed using Wilcoxon signed rank test. Result and Discussion: The mean total AMS Score reduced from 36 to 22.9, with a considerable reduction in somatic (14.2 to 9.45), psychological (12 to 7.4) and sexual subscales (9.65 to 6.05). The mean serum total testosterone value improved from 321.985 ng/dL to 399.839 ng/dL. Here, the treatment protocol was targeted at improving the Śukra Sārata by removing the Śukravāha Sṛotōvigunyam. The drugs in Nārasimha Rasāyana having action at levels of Agni, Sṛōtas and Dhātu, along with the specific affinity of the formulation towards the Śukravāha Srōtas ameliorated this condition by improving the physical, psychological, immunological and sexual domains in the individual. Conclusion: This treatment protocol helped in a correction the somatic, psychological and sexual symptoms in the individual with TD along with improving testosterone values with a statistical significance of p-value <0.05.