The Efficacy Of Intrasound Therapy On The Acute Tendon Injury

Abstract

Objective: The study investigated the effects of the low and high intensity Intrasound therapy (IRT) on tenocyte proliferation and oxidative stress in healing tendon.Methodology: Twenty male rats were divided randomly into four groups. Group 1; intact animals with no induced injury and no treatment, Group 2; had induced crush injury without IRT treatment, Group 3; had crush injury with low intensity IRT and Group 4; had crush injury with high intensity IRT. Treatment commenced 24 hours post-injury on alternate days for 10 days. On the 11 day post injury, the animals were sacrificed and the tendons excised and processed for histological study and Malondialdehyde (MDA) evaluation. Statistical analysis of tenocyte and MDA counts was done using ttest and analysis of variance (ANOVA).Results: Results show a statistical significant difference in the tenocyte and MDA counts among the four groups. Analysis of the mean tenocyte counts and MDA between the low intensity IRT (group 3) and high intensity IRT (group 4) reveals a significance difference (p 0.05) for tenocyte counts.Conclusion: The study does suggest that IRT may be a treatment option to be considered in the treatment of acute tendon injuries considering its beneficial effects on healing and a reduction in the oxidative stress in healing tendon. Also this modality is an area waiting to be explored, especially the molecular effects on healing as well as the biological mechanisms of action.