Abstract
BackgroundAlcohol use is a major public health challenge in France, where at the age of 17 half the young people report an episode of severe alcohol intoxication in the month preceding the survey. Numerous prevention programmes have a general objective, but in adolescence individual vulnerabilities towards addictions differ significantly with personality traits. Prevention targeting personality traits enables work on risk factors for addictive behaviours, and has shown genuine efficacy.Among existing programmes, PREVENTURE has shown an effect on the reduction in alcohol consumption by targeting four personality traits: impulsivity, sensation-seeking, negative thoughts and anxiety. This programme has been tested on samples recruited in adolescent populations in school environments, identifying adolescents at risk, but it has not been tested on a more targeted recruitment of adolescents seen in consultation.MethodsThe main hypothesis of this study is that the targeted prevention programme PREVENTURE will have an impact on the prevalence of binge-drinking episodes. The secondary hypotheses explore other factors such as associated substance use, anxiety and depression, as well as the acceptability of the programme. This article presents the study protocol of “PREVADO” study.We intend to assess the impact of the targeted intervention programme PREVENTURE on the prevalence of binge-drinking episodes among adolescents aged 14 to 17 years consulting in one of the participating centres or referred by a school doctor. The study will be prospective, randomised, controlled and open-label, and will comprise an intervention group and a control group.The adolescents will then be followed and assessed 1, 3, 6 and 12 months after the intervention.The study needs to include 700 subjects in order to reach 340 adolescents randomised, 170 in each group. It will concern 33 centres.DiscussionThis project could favour the targeting of addictive behaviours among vulnerable adolescents, and its application on a larger scale could be envisaged.Trial registrationThe Trial registration number is NCT04599270, and it was registered on the ClinicalTrials.gov public website.
Highlights
Alcohol use is a major public health challenge in France, where at the age of 17 half the young people report an episode of severe alcohol intoxication in the month preceding the survey
Alcohol consumption tends to emerge during adolescence, and is especially risky for adolescents given its impact on the developing brain [1]
Aim of the study The main objective of the current study is to evaluate the impact of the Preventure program on the prevalence of binge-drinking episodes among adolescents aged between 14 to 17 and at risk of developing problematic alcohol use, in comparison with usual follow-up care
Summary
Alcohol use is a major public health challenge in France, where at the age of 17 half the young people report an episode of severe alcohol intoxication in the month preceding the survey. Prevention targeting personality traits enables work on risk factors for addictive behaviours, and has shown genuine efficacy. PREVENTURE has shown an effect on the reduction in alcohol consumption by targeting four personality traits: impulsivity, sensation-seeking, negative thoughts and anxiety. This programme has been tested on samples recruited in adolescent populations in school environments, identifying adolescents at risk, but it has not been tested on a more targeted recruitment of adolescents seen in consultation. Alcohol use is considered as a leading risk factor in the global burden of disease and causes substantial damage to health [1,2,3]. Evidence suggests that an early onset of alcohol use increases the risk of alcohol use disorders in later life and comorbid mental health problems [6]
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