Abstract
The prevalence of insomnia is rising in today's culture under the influence of many factors. However, experts have long been concerned about the negative consequences and effects of hypnotic medicines. Currently, more and more researchers are focusing on the effects of drugs that target orexin receptors on sleep. Both daridorexant and Suvorexant are two effective dual orexin receptor antagonists in treating insomnia. According to the data collected from Google Scholar, JSTOR, NCBI, and PMC, the comparison of the effectiveness and the abuse potential between daridorexant and suvorexant is concluded. Suvorexant already is a common medicine for patients. The best dose for suvorexant is 30/40mg. Suvorexant has some unserious side-effects like nasopharyngitis. Daridorexant is a relatively new drugs that just enter the market in 2022. It has more function than Suvorexant like improving day-time function and sleep structure. The best dose for daridorexant is 50 mg. Daridorexant has unserious side-effects like fatigue and somnolence.
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