Abstract
Synthetic color is added to foods to replace natural color lost during processing. It is causes health problems mainly in children that considered Avery venerable group. This study was carried out investigate the effect of using color foods (Color fruit juice for 6 - 12 hr. Tomato ketchup potato chips (TKPC) color sweet and color chocolate at low (15%) and high (30%)) concentration on serum biochemical, WBC (white blood cell)and histopathology of liver and kidney of rats for 13 week. The results indicated that no significant change in body weight gain, serum glucose, HDL and LDL cholesterol. TKPC (30%) showed that significant increase in total cholesterol (TC), triacylglycerol (TG). Low and high concentration of color chocolate and color sweet was exhibited significant increase of TG. The level of ALT and AST was significant increase of rat’s administration color fruit juice (for 12 hr.) and TKPC at 30%. High concentration of color foods and long time administration of color fruit juice showed significant increase in serum creatinine and albumin compared to control group. Both low and high consumed of color foods exhibited significant decrease in liver GSH. High concentration of color foods lead to increase number of WBC as the result to the response of the immune system to the inflammation. Color foods were reveled change in histological structure of liver and kidney. In conclusion, the use synthetic color in various foods has adverse effect on some of biochemical analysis; and the liver and kidney histopathological structure.
Highlights
Color is an important characteristic and selection criterion for choice
This study was carried out investigate the effect of using color foods (Color fruit juice for 6 - hr—Tomato ketchup potato chips (TKPC)—color sweet and color chocolate at low (15%) and high (30%)) concentration on serum biochemical, white blood cell (WBC) and histopathology of liver and kidney of rats for week
High concentration of color foods and long time administration of color fruit juice showed significant increase in serum creatinine and albumin compared to control group
Summary
Color is an important characteristic and selection criterion for choice. The natural and synthetic color additives were used extensively to color foods, drugs and cosmetics [1] because low cost and high tinctorial power [2].Color additives have long been a part of human cultural. Color is an important characteristic and selection criterion for choice. The natural and synthetic color additives were used extensively to color foods, drugs and cosmetics [1] because low cost and high tinctorial power [2]. Color additives have long been a part of human cultural. Ancient Egyptian writing mention the use of drug colorants and historians estimate that food colors likely emerged quality of food product. The total world colorant production is estimated to be 8,000,000 tons per year [3]. The use of food dyes is at least controversial because they are only of essential role. Many of them have been related to health problems mainly in children that are considered a very vulnerable group [4]
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