Abstract

The effects of therapeutic hypothermia in patients in ROSC (Return of Spontaneous Circulation): Appropriate or ineffective treatment? A literature critical review

Highlights

  • Induction of moderate hypothermia (28 Á/32 8C) before cardiac arrest has been used successfully since the 1950s to protect the brain against the global ischaemia that occurs during some open-heart surgery

  • All members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest. This statement has been co-published in the 8 July 2003, issue of Circulation. This statement was approved by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation in April 2003

  • There seems to be good evidence (Level 1 [see Appendix A]) to recommend the use of induced mild hypothermia in comatose survivors of out-of-hospital cardiac arrest caused by ventricular fibrillation (VF)

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Summary

ILCOR recommendations

On the basis of the published evidence to date, the Advanced Life Support (ALS) Task Force of the International Liaison Committee on Resuscitation. All members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest. This statement has been co-published in the 8 July 2003, issue of Circulation. This statement was approved by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation in April 2003. Such cooling may be beneficial for other rhythms or in-hospital cardiac arrest

Introduction
Clinical studies
Mechanisms of action
Selection of patients
Timing of cooling
Cooling techniques and monitoring
Use of therapeutic hypothermia in children
Findings
Summary
Full Text
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