Abstract
1. The effects of the externally applied insecticide decamethrin on nerve excitability was studied on the giant axons of Myxicola infundibulum. 2. Membrane resting potential was only slightly reduced; Spike amplitudes were irreversibly reduced by 8–12%. 3. Voltage-clamp analysis showed a reduction of both early transient and late steady-state conductances. Kinetic effects were a prolongation of the time to peak early transient current and a slowing down of the first component of sodium tail current. 4. These results present similarities with allethrin-treated squid axons. The mechanism of action of pyrethroids is discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Comparative Biochemistry and Physiology. Part C, Comparative Pharmacology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
